Programmable Drug Delivery

Turning Oral Films
into Programmable
Therapeutic Platform

September 2025

Programmable Drug Delivery

Turning Oral Films
into Programmable
Therapeutic Platform

September 2025

The ODF* Breakthrough

Thin oral drug delivery films that release Active Pharmaceutical Ingredients (APIs) upon dissolving in the mouth

Fast-Acting Impact

Direct absorption through the oral mucosa for rapid therapeutic effects

Precise Dosing

Enhanced stability and lower dosage needs through controlled delivery

Bypasses First-Pass Metabolism

Fewer systemic side effects by avoiding liver metabolism

Safety & Compliance

Fewer systemic side effects by avoiding liver metabolism

Patient-Friendly

Ideal for pediatric, geriatric, and dysphagic populations

Portable & Convenient

Discreet use, no water required – perfect for on-the-go medication

*ODF: , offering a fast, convenient, and patient-friendly alternative to traditional tablets or liquids.

The ODF* Breakthrough

The ODF* Breakthrough

Thin oral drug delivery films that release Active Pharmaceutical Ingredients (APIs) upon dissolving in the mouth

Fast-Acting Impact

Direct absorption through the oral mucosa for rapid therapeutic effects

Precise Dosing

Enhanced stability and lower dosage needs through controlled delivery

Bypasses First-Pass Metabolism

Fewer systemic side effects by avoiding liver metabolism

Safety & Compliance

Fewer systemic side effects by avoiding liver metabolism

Patient-Friendly

Ideal for pediatric, geriatric, and dysphagic populations

Portable & Convenient

Discreet use, no water required – perfect for on-the-go medication

*ODF: Oral Drug Films

ODF Revolution Lingered Due to Tech Constraints

Narrow Therapeutic Impact

Restricted APIs capacity per strip (<50 mg)

Limited Release Control

Short absorption window (few minutes)

Limited API Flexibility

Poor handling of conflicting active ingredients

High Manufacturing Complexity & Cost

solvent-casting processes dominate

ODF Revolution Lingered Due to Tech Constraints

ODF

Those constraints have prevented ODF solutions from offering a much wider set of efficient applications

Narrow Therapeutic Impact

Restricted APIs capacity per strip (<50 mg)

Limited Release Control

Short absorption window (few minutes)

Limited API Flexibility

Poor handling of conflicting active ingredients

High Manufacturing Complexity & Cost

solvent-casting processes dominate

Introducing P-ODF

The first Programmable Platform,
Disrupting Drug Delivery

Dosage Quantities

Up to (exceptional) 150mg

Full Release Control

Flexible Time Patterns,
minutes to 12 hours

Multi API Mix

Introducing conflicting materials

Flexible Manufacturing Process

Allows small and large tailored batches per need

 

Introducing
P-ODF

The first Programmable Platform,
Disrupting Drug Delivery

Dosage Quantities

Up to (exceptional) 150mg

Full Release Control

Flexible Time Patterns,
minutes to 12 hours

Multi API Mix

Introducing conflicting materials

Flexible Manufacturing Process

Allows small and large tailored batches per need

 

Novel Enabling Technologies

P-ODF uses a proprietary biological and chemical programming mechanism with breakthrough architectural designs that enable unprecedented control over drug delivery.

Swelling Patch Technology

Hygroscopic polymer swells with humidity exposure, forming a gel for controlled, sustained API release over extended periods.

Multilayer 3D Patch

A novel manufacturing process enabling ultra-thin laminated layers, each carrying distinct APIs or functional roles.

Micro-Reservoirs (Wells)

Perforated layers form reservoirs for distinct APIs, preventing problematic interactions and enabling complex drug combinations.

Flexible & Cost-Effective Manufacturing

Reliable hot melt extrusion process enabling scalable, cost-effective production with consistent quality and precision.

Contact Us

PharMedica welcomes your comments, questions and inquiries.

Pharmedica LTD.

3 Pinchas Sapir Street
Science Park
Ness Ziona 7403626
Israel