Pharmedica

Turning Oral Films
into Programmable Therapeutic Platform

Reprogramming oral drug delivery

September 2025

The ODF* Breakthrough

Thin oral drug delivery films that release Active Ingredients (APIs) upon dissolving in the mouthPharmaceutical

Fast-Acting Impact

Direct absorption through the oral mucosa for rapid therapeutic effects

Bypasses First-Pass Metabolism

Fewer systemic side effects by avoiding liver metabolism

Portable & Convenient

Discreet use, no water required – perfect for on-the-go medication

Precise Dosing

Enhanced stability and lower dosage needs through controlled delivery

Patient-Friendly

Ideal for pediatric, geriatric, and dysphagic populations

Safety & Compliance

Hard to misuse with no overdose risk

*ODF: Thin oral drug delivery films that release Active Pharmaceutical Ingredients (APIs) upon dissolving in the mouth, offering a fast, convenient, and patient-friendly alternative to traditional tablets or liquids.

ODF Revolution Lingered Due to Tech Constraints

Traditional ODF Limitations

  • Narrow Therapeutic Impact Restricted APIs capacity per strip (<50 mg)
  • Limited API Flexibility Poor handling of conflicting active ingredients
  • Limited Release Control Short absorption window (few minutes)
  • High Manufacturing Complexity & Cost Solvent-casting processes dominate

These constraints have prevented ODF solutions from offering a much wider set of efficient applications in various medical fields, limiting their potential to transform drug delivery across multiple therapeutic areas.

Introducing P-ODF

The First Programmable Platform, Disrupting Drug Delivery

Revolutionary Capabilities

  • Dosage Quantities Up to exceptional 150mg per strip
  • Multi-API Mix Including conflicting materials in one platform
  • Full Release Control Flexible time patterns, from minutes to 12 hours
  • Flexible Manufacturing Process Allows small and large tailored batches per need

One Platform for All Applications

A unified solution that adapts to diverse therapeutic needs

Novel Enabling Technologies

P-ODF uses a proprietary biological and chemical programming mechanism with breakthrough architectural designs that enable unprecedented control over drug delivery.

Swelling Patch Technology

Hygroscopic polymer swells with humidity exposure, forming a gel for controlled, sustained API release over extended periods.

Multilayer 3D Patch

A novel manufacturing process enabling ultra-thin laminated layers, each carrying distinct APIs or functional roles.

Micro-Reservoirs (Wells)

Perforated layers form reservoirs for distinct APIs, preventing problematic interactions and enabling complex drug combinations.

Flexible & Cost-Effective Manufacturing

Reliable hot melt extrusion process enabling scalable, cost-effective production with consistent quality and precision.